Oxidative Stress and Age-Related NeurodegenerationAuthor:
Publisher: CRC Press
Publish date: November 2005
Covers the most recent developments in age-related neurodegenerative disorders Describes experimental evidence supporting the role of oxidative stress in these disorders Explores the effects of oxidative stress and how they can be addressed Discusses the similarities and differences between aging and neurodegeneration in terms of susceptibility to oxidative stress Examines the role of specific natural micronutrients and antioxidantsOxidative Stress and Age-Related Neurodegeneration is one volume in the highly respected Oxidative Stress and Disease Series from CRC Press. This series contains the work of historical pioneers and the world's cutting-edge researchers in free radicals, antioxidants, phytonutrients, AIDS, neurodegenerative diseases, and other related health concerns of modern society. A complete list of titles in the series can be found at www.crcpress.com. Despite the progress being made by researchers, Alzheimer's disease, along with other age-related neurodegenerative disorders, continues to exact a tremendous toll on our society. However, we are beginning to see a relationship that ties degenerative disorders to oxidative stress and lifestyle, suggesting the possibility for prevention and intervention through changes of individual habits, especially with regard to diet. Oxidative Stress and Age-Related Neurodegeneration brings together expert researchers involved with recent developments across a variety of fields. In looking at causation, prevention, and therapy, they offer contributions addressing these questions: · What similarities and differences exist between normal aging and disease-related neurodegeneration in terms of susceptibility to and effects of oxidative stress? · How can oxidative stress or its effects be attenuated? · Do antioxidants prevent or slow the progress of the disease? · Is there any role for natural micronutrients in the attenuation of oxidative stress and prevention of age-related neurodegeneration? Some chapters look at the various ways research is getting to the core of neurodegenerative disease, including the use of proteomics, comparisons to related diseases, and examinations at the cellular and molecular levels. Other chapters focus on specific antioxidants and nutrients cited as being impactful, such as those found in Gingko biloba, green tea, blueberries, and grape seed extract. Researchers in academia, industry, and clinical medicine, as well as students and scholars will find use for this timely collection, either as an introduction to our current understanding of neurodegeneration or as a reference for further research. Clinicians will also benefit, as this book explains the basis for many of the latest approaches to prevention and therapy.