Genomics and Proteomics in NutritionAuthor:
Publisher: CRC Press
Publish date: November 2004
Investigates the latest proteomic studies for a clear understanding of the role of nutrients and drugs in nutrient and cellular metabolism Presents selected examples showcasing the effect of phytochemicals on gene expression in different model systems Identifies molecular markers associated with various disease states for improved diagnostic and treatment regimens Familiarizes clinical investigators with the day-to-day problems encountered in the design, implementation, and evaluation of microarray analysis of clinical samples and provides the background necessary to develop solutions to these problems With contributions from 66 world-renowned authorities on the subject, Genomics and Proteomics in Nutrition focuses on the effect of genetic expression on protein production, establishing links between gene expression and nutrition, the influence of micro- and macronutrients on cellular homeostasis, and the relationship between diet, genetic predisposition, and human disease. Applying innovations in microarray technology to clinical practice, this reference explores advances in our understanding of obesity, birth defects, and cancer, and shows how bioinformatics and functional genomic databases can transform molecular biology research using a yeast ELO2/ human HELO1 protein cloning example.